SCHEMBL19982708

SCHEMBL19982708

CN(CCI)c1nc(N(CCI)CCI)nc(N(CCI)CCI)n1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
SLC29A1 Q99808 1/20 0.34
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
THRB P10828 1/20 0.32
BLM P54132 1/20 0.32
CREBBP Q92793 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19982856 0.79 MAPT (0.55) MAPTSMN1; SMN2SLC29A1LMNA
SCHEMBL20991400 0.74 MAPT (0.55) MAPTSMN1; SMN2SLC29A1LMNACYP1A2
SCHEMBL18460471 0.74 MAPT (0.55) MAPTSMN1; SMN2SLC29A1LMNACYP1A2
SCHEMBL18460079 0.73 TDP1 (0.38) MAPTSMN1; SMN2SLC29A1LMNACYP1A2
SCHEMBL21569764 0.70 SMN1; SMN2 (0.35) MAPTSMN1; SMN2SLC29A1LMNACYP1A2
SCHEMBL4151814 0.67 LMNA (0.65) SMN1; SMN2LMNACYP1A2THRBBLM
SCHEMBL12905000 0.66 CRHR1 (0.54) MAPTSMN1; SMN2SLC29A1
SCHEMBL1033204 0.66 SLC29A1 (0.53) MAPTSMN1; SMN2SLC29A1LMNATHRB
SCHEMBL1031875 0.65 CA12 (0.46) MAPTSLC29A1LMNACYP1A2THRB
SCHEMBL11766112 0.65 SLC29A1 (0.52) MAPTSLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180079868-A1 QUANTUM DOT-CONTAINING COMPOSITION, WAVELENGTH CONVERSION MEMBER, BACKLIGHT UNIT, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2018-03-22 US disclosed