Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MC4R | P32245 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | AHCY | P23526 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19975094 | 0.84 | RXFP1 (0.53) | ALDH1A1HPGDLMNA | |
| SCHEMBL1231292 | 0.76 | CYP1A2 (0.65) | NAMPTTSHRCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL15651624 | 0.75 | ALDH1A1 (0.58) | NAMPTUSP2ALDH1A1HPGDHDAC1 | |
| SCHEMBL29738559 | 0.73 | NAMPT (0.59) | NAMPTEPHX1TSHRCYP1A2CYP2D6 | |
| SCHEMBL15939311 | 0.73 | NAMPT (0.59) | NAMPTEPHX1TSHRCYP1A2CYP2D6 | |
| SCHEMBL4161846 | 0.73 | HDAC6 (0.60) | NAMPTMAOAKDM1AALDH1A1HPGD | |
| SCHEMBL15651019 | 0.72 | RECQL (0.53) | NAMPTTSHRCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4854629 | 0.71 | NAMPT (0.76) | NAMPTMAOBHPGD | |
| SCHEMBL2368296 | 0.70 | KIF11 (0.53) | NAMPTTSHRCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2065945 | 0.70 | NAMPT (0.50) | NAMPTTSHRCYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050631-A1 | ANTIVIRAL COMPOUNDS | HAPLOGEN GMBH (AT) | 2018-03-22 | — | — | WO | disclosed |