Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NMT2 | O60551 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19975244 | 0.87 | TSHR (0.49) | TSHRRAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL19974968 | 0.84 | TSHR (0.51) | TSHRRAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL19975271 | 0.80 | TSHR (0.52) | TSHRRAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8036861 | 0.77 | TSHR (0.56) | TSHRRAB9AALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL8036865 | 0.77 | TSHR (0.56) | TSHRRAB9AALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL28316771 | 0.72 | MMP9 (0.43) | SMN1; SMN2L3MBTL1 | |
| SCHEMBL1338859 | 0.71 | TSHR (0.44) | TSHRRAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL13368331 | 0.69 | TARBP2 (0.42) | TSHRRAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL13909205 | 0.69 | TSHR (0.40) | TSHRALDH1A1KDM4EPOLBTP53 | |
| SCHEMBL28316772 | 0.69 | MMP9 (0.46) | TSHRSMN1; SMN2MAPTPOLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050631-A1 | ANTIVIRAL COMPOUNDS | HAPLOGEN GMBH (AT) | 2018-03-22 | — | — | WO | disclosed |