Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP1 | O94782 | 1/20 | 0.40 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036861 | 1.00 | TSHR (0.56) | TSHRALDH1A1MAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL7219023 | 0.85 | USP1 (0.42) | TSHRALDH1A1SMN1; SMN2CYP2D6USP1 | |
| SCHEMBL8021171 | 0.85 | USP1 (0.42) | TSHRALDH1A1SMN1; SMN2CYP2D6USP1 | |
| SCHEMBL19975271 | 0.85 | TSHR (0.52) | TSHRALDH1A1MAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL7227003 | 0.85 | USP1 (0.42) | TSHRALDH1A1SMN1; SMN2CYP2D6USP1 | |
| SCHEMBL19974968 | 0.84 | TSHR (0.51) | TSHRALDH1A1MAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL14543852 | 0.82 | USP1 (0.42) | TSHRALDH1A1MAPK1SMN1; SMN2USP1 | |
| SCHEMBL19975244 | 0.82 | TSHR (0.49) | TSHRALDH1A1MAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL7221650 | 0.82 | PDCD1 (0.42) | TSHRALDH1A1SMN1; SMN2NPSR1RAB9A | |
| SCHEMBL5160271 | 0.80 | USP1 (0.47) | MEN1CYP1A2CYP2C19KMT2AUSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090951-A | Methods for the preparation of novel sidechain-bearing taxanes and intermediates | POSS MICHAEL A (US) | 2000-07-18 | — | — | US | disclosed |