Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 17/20 | 1.00 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.71 |
| ▸ | ESR1 | P03372 | 1/20 | 0.70 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.70 |
| ▸ | PGR | P06401 | 1/20 | 0.70 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.70 |
| ▸ | AR | P10275 | 1/20 | 0.70 |
| ▸ | THRA | P10827 | 1/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | MAOB | P27338 | 1/20 | 0.63 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.63 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.63 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1746663 | 0.86 | FFAR1 (0.82) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL1743642 | 0.85 | FFAR1 (0.74) | FFAR1FFAR4AKR1B1ESR1NR3C1 | |
| SCHEMBL1744653 | 0.84 | FFAR1 (1.00) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL1744939 | 0.84 | FFAR1 (1.00) | FFAR1FFAR4AKR1B1 | |
| Benzyloxyphenylpropanoic Acid SCHEMBL1134648 | 0.84 | FFAR1 (1.00) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL12570735 | 0.83 | FFAR1 (0.85) | FFAR1FFAR4AKR1B1THRATHRB | |
| SCHEMBL1746573 | 0.83 | FFAR1 (0.78) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL1747107 | 0.83 | FFAR1 (1.00) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL1745431 | 0.82 | FFAR1 (0.70) | FFAR1FFAR4AKR1B1ESR1NR3C1 | |
| SCHEMBL1745467 | 0.82 | FFAR1 (1.00) | FFAR1FFAR4AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960369-B2 | Receptor function regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-06-14 | — | — | US | disclosed |
| US-20090012093-A1 | Receptor Function Regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-01-08 | — | — | US | disclosed |
| EP-1559422-A1 | RECEPTOR FUNCTION CONTROLLING AGENT | Takeda Pharmaceutical Company Limited (JP) | 2005-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012093-A1 | Receptor Function Regulator | GPR119, GIPR, INSR | FFAR1 33/4885FFAR4 44/4885AKR1B1 1186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.