Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29901519 | 1.00 | TRPA1 (0.31) | TRPA1 | |
| Hydrochloric Acid SCHEMBL7403491 | 0.98 | TRPA1 (0.31) | TRPA1 | |
| Ammonia Solution, Strong SCHEMBL27596721 | 0.98 | TRPA1 (0.31) | TRPA1 | |
| SCHEMBL27543379 | 0.98 | TRPA1 (0.31) | TRPA1 | |
| SCHEMBL433359 | 0.98 | TRPA1 (0.31) | TRPA1 | |
| SCHEMBL27611235 | 0.98 | TRPA1 (0.31) | TRPA1 | |
| Hydrogen Sulfide SCHEMBL27732874 | 0.98 | TRPA1 (0.31) | TRPA1 | |
| Cycloheptane SCHEMBL27301709 | 0.94 | — | — | |
| Dimethyl Sulfoxide SCHEMBL8008395 | 0.89 | — | — | |
| Pyridine SCHEMBL28084682 | 0.89 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6690 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121846104-B | Application of benzothiazepine compound in preparation of medicines for treating cancers | 昆明医科大学 | 2026-05-22 | — | — | CN | claimed |
| EP-4648851-A1 | SUBSTITUTED (HETERO)ANILINES AND THEIR USE | Astrazeneca AB (SE) | 2025-11-19 | — | — | EP | claimed |
| WO-2025111482-A1 | COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS | BEXSON BIOMEDICAL, INC. (US) | 2025-05-30 | — | — | WO | claimed |
| US-20240417673-A1 | GIANT ORGANELLES RECOVERY AND USE THEREOF | PARIS SCIENCES ET LETTRES (FR) | 2024-12-19 | — | — | US | claimed |
| WO-2024149728-A1 | SUBSTITUTED (HETERO)ANILINES AND THEIR USE | ASTRAZENECA AB (SE) | 2024-07-18 | — | — | WO | claimed |
| CN-118290362-A | Process for preparing benzothiazepine isomers | 山东新华制药股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| WO-2024131886-A1 | BENZOTHIAZEPINE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 甫康（上海）健康科技有限责任公司 | 2024-06-27 | — | — | WO | claimed |
| CN-118239945-A | Benzothiazepine compound and preparation method and application thereof | 甫康（上海）健康科技有限责任公司 | 2024-06-25 | — | — | CN | claimed |
| WO-2024102758-A2 | N-(N-AMINOALKYL)PHENANTHRIDIUNIUM SERIES OF CHLORIDE-SENSITIVE FLUOROPHORES AND METHODS OF USE THEREOF | THE GENERAL HOSPITAL CORPORATION (US) | 2024-05-16 | — | — | WO | claimed |
| CN-117946028-A | Synthesis method of 1, 4-benzothiazepine compound | 南通大学 | 2024-04-30 | — | — | CN | claimed |
| US-4552695-A | Process for production of diltiazem hydrochloride | SHIONOGI & CO., LTD. (JP) | 1985-11-12 | — | — | US | claimed |
| EP-0158303-A2 | A process for the preparation of benzothiazepin derivatives | ABIC LTD. (IL) | 1985-10-16 | — | — | EP | claimed |
| EP-0158340-A2 | Novel 1,5-benzothiazepine derivative, processes for preparing the same and pharmaceutical compositions | Tanabe Seiyaku Co., Ltd. (JP) | 1985-10-16 | — | — | EP | claimed |
| EP-0081234-B1 | NOVEL METHOD OF PREPARING BENZOTHIAZEPINE DERIVATIVES | Tanabe Seiyaku Co., Ltd. (JP) | 1985-09-25 | — | — | EP | claimed |
| US-4539151-A | Benzothiazepine derivatives and their method of preparation | MITSUI TOATSU CHEMICALS, INC. (JP) | 1985-09-03 | — | — | US | claimed |
| US-4539150-A | HYPOTENSIVE AGENTS, SULFIDING, CYCLIZATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1985-09-03 | — | — | US | claimed |
| EP-0137083-A1 | 1,5-Benzothiazepine derivatives and production thereof | HAMARI YAKUHIN KOGYO KABUSHIKI KAISHA also known as HAMARI CHEMICALS, LTD. (JP) | 1985-04-17 | — | — | EP | claimed |
| US-4490292-A | 1,5-Benzothiazepine derivatives and production thereof | HAMARI CHEMICALS, LTD. (JP) | 1984-12-25 | — | — | US | claimed |
| US-4438035-A | Method of preparing benzothiazepine derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1984-03-20 | — | — | US | claimed |
| EP-0081234-A1 | Novel method of preparing benzothiazepine derivatives | Tanabe Seiyaku Co., Ltd. (JP) | 1983-06-15 | — | — | EP | claimed |