Pyridine

Pyridine

SCHEMBL28084682

C1=Cc2ccccc2SN=C1.c1ccncc1

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
NAPRT Q6XQN6 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29901519 0.89 TRPA1 (0.31)
SCHEMBL19983 0.89 TRPA1 (0.31)
SCHEMBL27543379 0.87 TRPA1 (0.31)
Hydrochloric Acid SCHEMBL7403491 0.87 TRPA1 (0.31)
SCHEMBL27611235 0.87 TRPA1 (0.31)
Hydrogen Sulfide SCHEMBL27732874 0.87 TRPA1 (0.31)
Ammonia Solution, Strong SCHEMBL27596721 0.87 TRPA1 (0.31)
SCHEMBL433359 0.87 TRPA1 (0.31)
Cycloheptane SCHEMBL27301709 0.84
Carbamic Acid SCHEMBL4912022 0.81 LMNA (0.36) TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105837564-A Pyridine-containing benzothiazepine derivatives, and preparation method and application thereof 贵州大学 2016-08-10 CN claimed
CN-105837564-B One kind benzothiazepines containing pyridine derivative, preparation method and the usage 贵州大学 2019-02-05 CN disclosed
CN-105837564-A Pyridine-containing benzothiazepine derivatives, and preparation method and application thereof 贵州大学 2016-08-10 CN disclosed