Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | PLA2G2C | Q5R387 | 7/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | CRAT | P43155 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24015929 | 0.84 | PLA2G2C (0.41) | CA12CA1CA2CA9PLA2G2C | |
| SCHEMBL24015829 | 0.84 | PLA2G2C (0.41) | CA12CA1CA2CA9PLA2G2C | |
| SCHEMBL24015921 | 0.84 | PLA2G2C (0.41) | CA12CA1CA2CA9PLA2G2C | |
| SCHEMBL17506705 | 0.83 | TAS1R3 (0.47) | MMP1MMP2CA12CA1CA2 | |
| SCHEMBL13888611 | 0.83 | TAS1R3 (0.47) | MMP1MMP2CA12CA1CA2 | |
| SCHEMBL25099320 | 0.81 | MMP1 (0.41) | MMP1MMP2CA12CA1CA2 | |
| SCHEMBL25587274 | 0.79 | CA1 (0.40) | MMP1MMP2CA12CA1CA2 | |
| SCHEMBL25587273 | 0.79 | CA1 (0.40) | MMP1MMP2CA12CA1CA2 | |
| SCHEMBL25587276 | 0.79 | CA1 (0.40) | MMP1MMP2CA12CA1CA2 | |
| SCHEMBL8367402 | 0.79 | TAS1R3 (0.46) | MMP1MMP2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2881394-B1 | CONDENSED RING HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO LTD (JP) | 2018-03-21 | — | — | EP | disclosed |