Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | CTSH | P09668 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19972765 | 0.93 | CTSK (0.56) | CTSKCTSHCTSB | |
| SCHEMBL19972768 | 0.93 | CTSK (0.56) | CTSKCTSHCTSB | |
| SCHEMBL23023464 | 0.92 | CTSK (0.55) | CTSKCTSHCTSB | |
| SCHEMBL17665993 | 0.86 | CTSK (0.55) | CTSKCTSHCTSB | |
| SCHEMBL17646358 | 0.86 | CTSK (0.55) | CTSKCTSHCTSB | |
| SCHEMBL25658991 | 0.85 | CTSK (0.46) | CTSKCTSH | |
| SCHEMBL17661708 | 0.82 | CTSK (0.49) | CTSKCTSHCTSB | |
| SCHEMBL17661705 | 0.82 | CTSK (0.49) | CTSKCTSHCTSB | |
| SCHEMBL19983290 | 0.79 | CTSH (0.41) | CTSKCTSH | |
| SCHEMBL19688639 | 0.79 | CTSK (0.43) | CTSKCTSHCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053353-A1 | KETONE INHIBITORS OF LYSINE GINGIPAIN | Cortexyme, Inc. (US) | 2018-03-22 | — | — | WO | disclosed |