Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.83 |
| ▸ | CTSL | P07711 | 1/20 | 0.83 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30716858 | 0.91 | CTSK (1.00) | CTSKCTSL | |
| SCHEMBL19983189 | 0.91 | CTSK (1.00) | CTSKCTSL | |
| SCHEMBL19983012 | 0.91 | CTSK (1.00) | CTSKCTSL | |
| SCHEMBL19983323 | 0.85 | CTSL (0.72) | CTSKCTSLFOLH1 | |
| SCHEMBL25658918 | 0.84 | CTSK (0.62) | CTSKCTSL | |
| SCHEMBL25658980 | 0.80 | CTSK (0.55) | CTSKCTSL | |
| SCHEMBL25658919 | 0.80 | CTSL (0.52) | CTSKCTSLFOLH1 | |
| SCHEMBL19982982 | 0.79 | CTSK (0.76) | CTSKCTSL | |
| SCHEMBL30716863 | 0.79 | CTSK (0.76) | CTSKCTSL | |
| SCHEMBL25658764 | 0.79 | CTSK (0.76) | CTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053353-A1 | KETONE INHIBITORS OF LYSINE GINGIPAIN | Cortexyme, Inc. (US) | 2018-03-22 | — | — | WO | disclosed |