Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19982905 | 0.91 | KDM4E (0.41) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL21779737 | 0.80 | KDM4E (0.37) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL19982878 | 0.79 | KDM4E (0.31) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL9759517 | 0.78 | KDM4E (0.32) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL9759509 | 0.78 | KDM4E (0.32) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL9759511 | 0.78 | KDM4E (0.32) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL19982879 | 0.78 | KDM4E (0.36) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL19983269 | 0.77 | KDM4E (0.35) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL178339 | 0.74 | KDM4E (0.42) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL2290730 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2881394-B1 | CONDENSED RING HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO LTD (JP) | 2018-03-21 | — | — | EP | disclosed |