Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178339 | 0.91 | KDM4E (0.42) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL17835279 | 0.82 | APLNR (0.36) | POLB | |
| SCHEMBL17490614 | 0.82 | APLNR (0.36) | POLB | |
| SCHEMBL17835280 | 0.82 | APLNR (0.36) | POLB | |
| SCHEMBL19983270 | 0.80 | KDM4E (0.36) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL19982879 | 0.80 | KDM4E (0.36) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL19983269 | 0.78 | KDM4E (0.35) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL765004 | 0.76 | — | — | |
| SCHEMBL1962749 | 0.76 | — | — | |
| SCHEMBL22144017 | 0.76 | APLNR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024035950-A1 | INHIBITORS OF KIF18A AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |
| EP-3252041-B1 | BIPYRIDINE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL | SUMITOMO CHEMICAL CO (JP) | 2020-03-04 | — | — | EP | disclosed |