Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983270 | 0.79 | KDM4E (0.36) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL1962180 | 0.75 | — | — | |
| SCHEMBL21779737 | 0.72 | KDM4E (0.37) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL9954 | 0.72 | — | — | |
| SCHEMBL28350494 | 0.72 | CYP1A2 (0.48) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL19982879 | 0.71 | KDM4E (0.36) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL18781636 | 0.71 | ALDH1A1 (0.34) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL22144017 | 0.71 | APLNR (0.34) | CYP1A2 | |
| SCHEMBL27375615 | 0.71 | APLNR (0.34) | CYP1A2 | |
| Ethylene SCHEMBL8002075 | 0.70 | CYP1A2 (0.48) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2881394-B1 | CONDENSED RING HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO LTD (JP) | 2018-03-21 | — | — | EP | disclosed |