Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16140056 | 0.82 | GRIA1 (0.41) | GRIA1GRIA2GRIA3GRIA4PDE4A | |
| SCHEMBL16140059 | 0.78 | GRIA1 (0.39) | GRIA1GRIA2GRIA3GRIA4KDM4E | |
| SCHEMBL12354602 | 0.77 | CYP2A6 (0.43) | GRIA1GRIA2GRIA3GRIA4CYP3A4 | |
| SCHEMBL672601 | 0.75 | GRIA1 (0.48) | GRIA1GRIA2GRIA3GRIA4PDE4A | |
| SCHEMBL16140063 | 0.75 | GRIA1 (0.36) | GRIA1GRIA2GRIA3GRIA4PDE4A | |
| SCHEMBL6985794 | 0.75 | GRIA1 (0.34) | GRIA1GRIA2GRIA3GRIA4PDE4A | |
| SCHEMBL13241079 | 0.71 | CYP2C19 (0.50) | GRIA1GRIA2GRIA3GRIA4PDE4A | |
| SCHEMBL7854609 | 0.71 | FYN (0.56) | GRIA1GRIA2GRIA3GRIA4PDE4A | |
| SCHEMBL6848672 | 0.71 | GRIA1 (0.37) | GRIA1GRIA2GRIA3GRIA4KDM4E | |
| SCHEMBL15202657 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018049465-A1 | METHOD OF RETARDING AN ETHYLENE RESPONSE | CURTIN UNIVERSITY OF TECHNOLOGY (AU) | 2018-03-22 | — | — | WO | disclosed |