Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 8/20 | 0.34 |
| ▸ | PARP1 | P09874 | 5/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.31 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.31 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.31 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.31 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.31 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.31 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.31 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.31 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739179 | 0.76 | PARP10 (0.41) | GRIA1CRBNPARP10PARP1PARP11 | |
| SCHEMBL9739665 | 0.75 | KDM4E (0.60) | CRBNPARP10PARP1PARP11KDM4E | |
| SCHEMBL15471727 | 0.75 | KDM4E (0.56) | PARP10PARP1PARP11KDM4EF7 | |
| SCHEMBL12354602 | 0.73 | CYP2A6 (0.43) | GRIA1GRIA2GRIA3GRIA4KDM4E | |
| SCHEMBL5040462 | 0.71 | DRD2 (0.55) | PARP10PARP1PARP11F7F3 | |
| SCHEMBL24795 | 0.71 | CYP3A4 (0.52) | KDM4EMTNR1AMTNR1BDRD4 | |
| SCHEMBL5048666 | 0.71 | DRD2 (0.56) | PARP10PARP1F7F3DRD2 | |
| SCHEMBL30468509 | 0.71 | DRD2 (0.55) | PARP10PARP1PARP11F7F3 | |
| SCHEMBL16140065 | 0.71 | GRIA1 (0.37) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL19983360 | 0.71 | GRIA1 (0.39) | GRIA1GRIA2GRIA3GRIA4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120172589-A1 | PROCESS FOR THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID | LES LABORATOIRES SERVIER (FR) | 2012-07-05 | — | — | US | disclosed |
| US-20120172589-A1 | PROCESS FOR THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID | LES LABORATOIRES SERVIER (FR) | 2012-07-05 | — | — | US | disclosed |
| WO-2011033194-A1 | NOVEL METHOD FOR SYNTHESIZING IVABRADINE AND THE ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID | LES LABORATOIRES SERVIER (FR) | 2011-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172589-A1 | PROCESS FOR THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID | CYP4F2, CYP2F1, CYP2D6 | GRIA1 1749/4885GRIA2 1470/4885GRIA3 2782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.