Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 3/20 | 0.47 |
| ▸ | COPS5 | Q92905 | 3/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | CSF1R | P07333 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | FLT4 | P35916 | 2/20 | 0.41 |
| ▸ | CLK2 | P49760 | 2/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
| ▸ | STK3 | Q13188 | 2/20 | 0.41 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.41 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29221148 | 0.98 | PSMD14 (0.46) | PSMD14COPS5PARP1PRKD3MAP4K4 | |
| SCHEMBL6615706 | 0.76 | NR4A2 (0.61) | PARP1PRKD3MAP4K4CDK1CSF1R | |
| SCHEMBL3272431 | 0.76 | PSMD14 (0.61) | PSMD14COPS5PARP1PRKD3MAP4K4 | |
| SCHEMBL3712379 | 0.76 | KDM4E (0.46) | PSMD14COPS5PARP1PRKD3MAP4K4 | |
| SCHEMBL30543147 | 0.76 | KDM4E (0.53) | PARP1PRKD3MAP4K4CDK1CSF1R | |
| SCHEMBL1258962 | 0.76 | KDM4E (0.52) | PARP1PRKD3MAP4K4CDK1CSF1R | |
| SCHEMBL29933523 | 0.76 | KDM4E (0.46) | PSMD14COPS5PARP1PRKD3MAP4K4 | |
| SCHEMBL317537 | 0.76 | KDM4E (0.53) | PARP1PRKD3MAP4K4CDK1CSF1R | |
| SCHEMBL3829932 | 0.76 | CCR1 (0.63) | PARP1PRKD3MAP4K4CDK1CSF1R | |
| SCHEMBL27082587 | 0.74 | PARP1 (0.43) | PSMD14COPS5PARP1PRKD3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053126-A1 | INHIBITION OF BMP SIGNALING, COMPOUNDS, COMPOSITIONS AND USES THEREOF | VANDERBILT UNIVERSITY (US) | 2018-03-22 | — | — | WO | disclosed |