Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.47 |
| ▸ | METAP2 | P50579 | 2/20 | 0.47 |
| ▸ | METAP1 | P53582 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30543147 | 1.00 | KDM4E (0.53) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL318769 | 0.81 | NR4A2 (0.68) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL29410781 | 0.81 | NR4A2 (0.68) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL6615706 | 0.76 | NR4A2 (0.61) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL317120 | 0.76 | HTR1A (0.56) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL3630037 | 0.76 | KDM4E (0.53) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL1245479 | 0.76 | KDM4E (0.54) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL19983428 | 0.76 | PSMD14 (0.47) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL2701957 | 0.76 | KDM4E (0.72) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL2515670 | 0.76 | NR4A2 (0.61) | KDM4EALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12612384-B2 | Heterocyclic CYP4A inhibitor compounds and compositions thereof | MBD Co., Ltd. (KR) | 2026-04-28 | — | — | US | disclosed |
| US-12611404-B2 | Aza-aryl 1H-pyrazol-1-yl benzene sulfonamides | CHEMOCENTRYX, INC. (US) | 2026-04-28 | — | — | US | disclosed |
| WO-2025090465-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-05-01 | — | — | WO | disclosed |
| EP-3558969-B1 | PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-09-18 | — | — | EP | disclosed |
| US-12077521-B2 | Pyrazole derivatives as MALT1 inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2024-09-03 | — | — | US | disclosed |
| US-20240287032-A1 | NOVEL HETEROCYCLIC COMPOUND AND USE THEREOF | MBD Co., Ltd. (KR) | 2024-08-29 | — | — | US | disclosed |
| US-20230339900-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-26 | — | — | US | disclosed |
| EP-4214199-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-07-26 | — | — | EP | disclosed |
| CN-116490503-A | Casein kinase 1 delta modulators | 詹森药业有限公司 | 2023-07-25 | — | — | CN | disclosed |
| WO-2022235091-A1 | NOVEL HETEROCYCLIC COMPOUND AND USE THEREOF | 엠비디 주식회사 | 2022-11-10 | — | — | WO | disclosed |
| US-5294622-A | Fungicides, insecticides, miticides | DOWELANCO (US) | 1994-03-15 | — | — | US | disclosed |
| WO-1994004526-A1 | 4-[2-(4-(2-PYRIDINYLOXY)PHENYL)ETHOXY]-QUINAZOLINE AND ANALOGUES THEREOF | DOWELANCO (US) | 1994-03-03 | — | — | WO | disclosed |
| WO-1993005050-A1 | 4-(ARALKOXY OR ARALKYLAMINO)PYRIDINE PESTICIDES_________________ | DOWELANCO (US) | 1993-03-18 | — | — | WO | disclosed |
| US-5114939-A | Amine or ether substitutes compounds of quinoline or cinnoline | DOWELANCO (US) | 1992-05-19 | — | — | US | disclosed |
| EP-0326331-A2 | Substituted quinolines and cinnolines | DowElanco (US) | 1989-08-02 | — | — | EP | disclosed |
| EP-0326328-A2 | Quinoline, quinazoline, and cinnoline derivatives | DowElanco (US) | 1989-08-02 | — | — | EP | disclosed |
| EP-0168812-A1 | 4-Amino-2-phenyl quinolines, methods and intermediates for their preparation and medicaments containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-01-22 | — | — | EP | disclosed |
| EP-0001175-A1 | 4-Aminoquinoline derivatives, a process for their preparation and pharmaceutical compositions containing them | JOHN WYETH & BROTHER LIMITED (GB) | 1979-03-21 | — | — | EP | disclosed |
| US-4057633-A | ANTIANXIETY, HYPOTENSIVE | THE UPJOHN COMPANY (US) | 1977-11-08 | — | — | US | disclosed |
| US-3992382-A | HYPERTENSION AND ANXIETY TREATMENT | THE UPJOHN COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240287032-A1 | NOVEL HETEROCYCLIC COMPOUND AND USE THEREOF | CYP4B1, CYP4A11, CYP3A4 | KDM4E 642/4885ALDH1A1 268/4885TDP1 3057/4885 |
| US-20230339900-A1 | CASEIN KINASE 1 DELTA MODULATORS | CSNK1D, CSNK1A1, CSNK2A1 | KDM4E 2449/4885ALDH1A1 1600/4885TDP1 1173/4885 |
| US-12612384-B2 | Heterocyclic CYP4A inhibitor compounds and compositions thereof | CYP4A11, CYP4B1, CYP4A22 | KDM4E 1396/4885ALDH1A1 217/4885TDP1 1533/4885 |
| US-12611404-B2 | Aza-aryl 1H-pyrazol-1-yl benzene sulfonamides | CCR1, CCR9, CCR8 | KDM4E 2895/4885ALDH1A1 2034/4885TDP1 4614/4885 |
| US-12077521-B2 | Pyrazole derivatives as MALT1 inhibitors | MALT1, PPP3R1, SQSTM1 | KDM4E 3526/4885ALDH1A1 2543/4885TDP1 428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.