Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 4/20 | 0.73 |
| ▸ | AHCY | P23526 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | NSD2 | O96028 | 2/20 | 0.58 |
| ▸ | DOT1L | Q8TEK3 | 5/20 | 0.58 |
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
| ▸ | DPP4 | P27487 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.57 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.57 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.57 |
| ▸ | GAPDH | P04406 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.57 |
| ▸ | STAT6 | P42226 | 1/20 | 0.57 |
| ▸ | PI4KA | P42356 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983463 | 1.00 | CARM1 (0.73) | CARM1AHCYATMNSD2DOT1L | |
| SCHEMBL6900816 | 0.86 | ATM (0.76) | CARM1AHCYATMDOT1LADORA1 | |
| SCHEMBL14906024 | 0.84 | CARM1 (1.00) | CARM1NSD2DOT1LEHMT2KMT2A | |
| SCHEMBL19983489 | 0.84 | CARM1 (1.00) | CARM1NSD2DOT1LEHMT2KMT2A | |
| SCHEMBL16156831 | 0.84 | CARM1 (1.00) | CARM1NSD2DOT1LEHMT2KMT2A | |
| SCHEMBL19983490 | 0.84 | CARM1 (0.82) | CARM1AHCYNSD2DOT1LEHMT2 | |
| SCHEMBL16154100 | 0.82 | CARM1 (0.75) | CARM1AHCYNSD2DOT1LEHMT2 | |
| SCHEMBL26453664 | 0.82 | CARM1 (0.76) | CARM1AHCYNSD2DOT1LEHMT2 | |
| SCHEMBL19111312 | 0.81 | AMD1 (0.67) | CARM1AHCYATMDOT1LKMT2A | |
| SCHEMBL19760477 | 0.81 | DOT1L (0.74) | CARM1AHCYNSD2DOT1LEHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043645-B2 | Adenosine analogs as methyltransferase inhibitors for treating cancer | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2024-07-23 | — | — | US | disclosed |
| US-20230135822-A1 | ADENOSINE ANALOGS AS METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2023-05-04 | — | — | US | disclosed |
| US-20210017216-A1 | ADENOSINE ANALOGS AS METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2021-01-21 | — | — | US | disclosed |
| US-10730903-B2 | Adenosine analogs as methyltransferase inhibitors for treating cancer | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2020-08-04 | — | — | US | disclosed |
| US-20190276488-A1 | ADENOSINE ANALOGS AS METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2019-09-12 | — | — | US | disclosed |
| WO-2018053313-A1 | ADENOSINE ANALOGS AS METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2018-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210017216-A1 | ADENOSINE ANALOGS AS METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | DIMT1, TPMT, MTAP | CARM1 62/4885AHCY 31/4885ATM 599/4885 |
| US-20190276488-A1 | ADENOSINE ANALOGS AS METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | DIMT1, TPMT, MTAP | CARM1 62/4885AHCY 31/4885ATM 599/4885 |
| US-12043645-B2 | Adenosine analogs as methyltransferase inhibitors for treating cancer | DIMT1, TPMT, MTAP | CARM1 62/4885AHCY 31/4885ATM 599/4885 |
| US-20230135822-A1 | ADENOSINE ANALOGS AS METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | DIMT1, TPMT, MTAP | CARM1 62/4885AHCY 31/4885ATM 599/4885 |
| US-10730903-B2 | Adenosine analogs as methyltransferase inhibitors for treating cancer | DIMT1, TPMT, MTAP | CARM1 62/4885AHCY 31/4885ATM 599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.