Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TPMT | P51580 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1635332 | 0.78 | IMPDH2 (0.37) | IMPDH2TDP1CYP3A4MAPTPDE4A | |
| SCHEMBL1052797 | 0.77 | TDP1 (0.39) | IMPDH2TDP1CYP3A4MAPTPDE4A | |
| SCHEMBL18090614 | 0.75 | TDP1 (0.38) | IMPDH2TDP1CYP3A4MAPTPDE4A | |
| SCHEMBL21937056 | 0.74 | TTR (0.33) | — | |
| SCHEMBL27846586 | 0.73 | TDP1 (0.45) | TDP1CYP3A4MAPTPDE4APDE4B | |
| SCHEMBL8935421 | 0.72 | ACHE (0.31) | IMPDH2 | |
| SCHEMBL2798555 | 0.71 | TDP1 (0.39) | IMPDH2TDP1CYP3A4MAPTPDE4A | |
| SCHEMBL12143217 | 0.71 | TDP1 (0.46) | IMPDH2TDP1CYP3A4MAPTPDE4A | |
| SCHEMBL20256643 | 0.71 | TDP1 (0.39) | IMPDH2TDP1CYP3A4MAPTPDE4A | |
| SCHEMBL5516691 | 0.71 | TDP1 (0.39) | IMPDH2TDP1CYP3A4MAPTPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11041046-B2 | Method for poly(phenylene ether) manufacture and associated poly(phenylene ether) | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2021-06-22 | — | — | US | disclosed |
| US-20180079863-A1 | METHOD FOR POLY(PHENYLENE ETHER) MANUFACTURE AND ASSOCIATED POLY(PHENYLENE ETHER) | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2018-03-22 | — | — | US | disclosed |