Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.58 |
| ▸ | FNTA | P49354 | 1/20 | 0.58 |
| ▸ | FNTB | P49356 | 1/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.58 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.49 |
| ▸ | GGT1 | P19440 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11138429 | 0.87 | ALDH1A1 (0.53) | ALDH1A1POLBGAACRHBPFNTA | |
| SCHEMBL5122460 | 0.84 | POLB (0.51) | ALDH1A1POLBGAACRHBPFNTA | |
| SCHEMBL1798 | 0.83 | CTNNB1 (0.71) | ALDH1A1CTNNB1HTTKDM4ETSHR | |
| SCHEMBL1656093 | 0.82 | TSHR (0.59) | ALDH1A1POLBCTNNB1KDM4ETSHR | |
| SCHEMBL5818265 | 0.82 | RXFP1 (0.50) | ALDH1A1POLBGAAKDM4EHPGD | |
| SCHEMBL370837 | 0.81 | ALDH1A1 (0.52) | ALDH1A1POLBGAACRHBPFNTA | |
| SCHEMBL4129945 | 0.81 | CTNNB1 (0.69) | ALDH1A1CTNNB1HTTKDM4ETSHR | |
| SCHEMBL8496446 | 0.81 | CTNNB1 (0.69) | ALDH1A1CTNNB1HTTKDM4ETSHR | |
| Bicarbonate SCHEMBL21517637 | 0.81 | CTNNB1 (0.69) | ALDH1A1CTNNB1HTTKDM4ETSHR | |
| SCHEMBL11875755 | 0.81 | CTNNB1 (0.69) | ALDH1A1CTNNB1HTTKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210401947-A1 | CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | SANOFI (FR) | 2021-12-30 | — | — | US | disclosed |
| US-20210401946-A1 | CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | SANOFI (FR) | 2021-12-30 | — | — | US | disclosed |
| US-11090364-B2 | Conjugates of a pharmaceutical agent and a moiety capable of binding to a glucose sensing protein | SANOFI (FR) | 2021-08-17 | — | — | US | disclosed |
| US-20190209656-A1 | CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | SANOFI (FR) | 2019-07-11 | — | — | US | disclosed |
| EP-3463480-A1 | CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | Sanofi (FR) | 2019-04-10 | — | — | EP | disclosed |
| CN-109562185-A | Novel conjugates of agents and moieties capable of binding to glucose-sensing proteins | 赛诺菲 | 2019-04-02 | — | — | CN | disclosed |
| US-8883789-B2 | Piperazine derivatives and their use as positive allosteric modulators of mGluR5 receptors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-11-11 | — | — | US | disclosed |
| US-20130158042-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-20 | — | — | US | disclosed |
| US-8389619-B1 | In-situ nanocomposites from polymerization of an aryloxybenzoic acid in the presence of detonation nanodiamond | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2013-03-05 | — | — | US | disclosed |
| US-7960471-B1 | Nanocomposites from in-situ polymerization of 3-phenoxy-benzoic acid in the presence of vapor-grown carbon nanofibers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2011-06-14 | — | — | US | disclosed |
| EP-0348002-B1 | Herbicidal acrylonitrile derivatives | SHELL INT RESEARCH (NL) | 1995-04-12 | — | — | EP | disclosed |
| US-5152825-A | HERBICIDAL 2-PYRIDYLOXY-BENZOYL-ACRYLONITRILES | SHELL INTERNATIONAL RESEARCH MAATSCHAPPIJ B.V. (NL) | 1992-10-06 | — | — | US | disclosed |
| US-4988385-A | Plant growth regulators, antigrowth agents for plants | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1991-01-29 | — | — | US | disclosed |
| EP-0348002-A2 | Herbicidal acrylonitrile derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11090364-B2 | Conjugates of a pharmaceutical agent and a moiety capable of binding to a glucose sensing protein | GPR119, SLC2A8, SLC2A4 | ALDH1A1 1514/4885POLB 4854/4885GAA 143/4885 |
| US-20190209656-A1 | CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | GPR119, SLC2A8, SLC2A4 | ALDH1A1 1514/4885POLB 4854/4885GAA 143/4885 |
| US-20210401946-A1 | CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | GPR119, SLC2A8, SLC2A4 | ALDH1A1 1514/4885POLB 4854/4885GAA 143/4885 |
| US-20210401947-A1 | CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | GPR119, SLC2A8, SLC2A4 | ALDH1A1 1514/4885POLB 4854/4885GAA 143/4885 |
| US-20130158042-A1 | NOVEL COMPOUNDS | GRM5, GRIK5, GRM1 | ALDH1A1 3952/4885POLB 4052/4885GAA 2631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.