Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | MPO | P05164 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983876 | 0.94 | CHRNB2 (0.43) | CHRNB2CHRNA7CHRNA4GPR84HTR2A | |
| SCHEMBL19984243 | 0.90 | GPR84 (0.46) | CHRNB2CHRNA7CHRNA4GPR84HTR2A | |
| SCHEMBL19983887 | 0.88 | GPR84 (0.43) | CHRNB2CHRNA7CHRNA4GPR84HTR2A | |
| SCHEMBL19983884 | 0.87 | GPR84 (0.41) | CHRNB2CHRNA7CHRNA4GPR84HTR2A | |
| SCHEMBL19983851 | 0.86 | CHRNB2 (0.47) | CHRNB2CHRNA7CHRNA4GPR84HTR2A | |
| SCHEMBL19984242 | 0.86 | HTR2A (0.44) | CHRNB2CHRNA7CHRNA4GPR84HTR2A | |
| SCHEMBL19983984 | 0.82 | GPR84 (0.41) | CHRNB2CHRNA7CHRNA4GPR84HTR2A | |
| SCHEMBL19983983 | 0.81 | GPR84 (0.44) | CHRNB2CHRNA7CHRNA4GPR84HTR2A | |
| SCHEMBL19984119 | 0.81 | GPR84 (0.53) | CHRNB2CHRNA7CHRNA4GPR84HTR2A | |
| SCHEMBL19983765 | 0.81 | GPR84 (0.43) | CHRNB2CHRNA7CHRNA4GPR84HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |