Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23992106 | 0.83 | MCL1 (0.36) | MCL1FAAHMMP1MMP2MMP3 | |
| SCHEMBL25683312 | 0.83 | MCL1 (0.36) | MCL1FAAHMMP1MMP2MMP3 | |
| SCHEMBL13267325 | 0.82 | MCL1 (0.35) | MCL1FAAHTSHR | |
| SCHEMBL13575850 | 0.80 | MCL1 (0.33) | MCL1KMT2AMEN1CA12CA1 | |
| SCHEMBL10703991 | 0.79 | FAAH (0.44) | MCL1FAAHKMT2AMEN1TSHR | |
| SCHEMBL30421139 | 0.78 | MCL1 (0.39) | MCL1FAAHKMT2AMMP1MMP2 | |
| SCHEMBL10330332 | 0.77 | MCL1 (0.38) | MCL1FAAHKMT2AMEN1 | |
| SCHEMBL1829003 | 0.77 | — | — | |
| SCHEMBL7318522 | 0.76 | — | — | |
| SCHEMBL27827133 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3526239-B1 | HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES | OLIPASS CORP (KR) | 2021-11-03 | — | — | EP | disclosed |
| WO-2021010723-A1 | MELANOPHILIN ANTISENSE OLIGONUCLEOTIDES | OLIPASS Cosmeceuticals Company (KR) | 2021-01-21 | — | — | WO | disclosed |
| WO-2018051175-A1 | SCN9A ANTISENSE OLIGONUCLEOTIDES | OLIPASS CORPORATION (KR) | 2018-03-22 | — | — | WO | disclosed |