Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GRK2 | P25098 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984522 | 0.96 | ALDH1A1 (0.38) | AAK1ALDH1A1KDM4EGLAMAPT | |
| SCHEMBL19984595 | 0.86 | ALDH1A1 (0.44) | AAK1ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL19984699 | 0.82 | ALDH1A1 (0.47) | AAK1ALDH1A1KDM4EKMT2AHTT | |
| SCHEMBL19984568 | 0.72 | ALDH1A1 (0.49) | ALDH1A1KDM4EGHSRPOLBHTT | |
| SCHEMBL19975006 | 0.68 | HCRTR1 (0.52) | ALDH1A1KDM4EPOLBHTTSMN1; SMN2 | |
| SCHEMBL19975007 | 0.68 | HCRTR1 (0.52) | ALDH1A1KDM4EPOLBHTTSMN1; SMN2 | |
| SCHEMBL3643939 | 0.66 | ALDH1A1 (0.48) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL9473812 | 0.66 | ALDH1A1 (0.48) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL7644709 | 0.65 | ALDH1A1 (0.47) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL22798963 | 0.65 | BRS3 (0.44) | ALDH1A1GHSRMAPTKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053157-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2018-03-22 | — | — | WO | disclosed |