Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.30 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984571 | 0.79 | POLB (0.35) | POLBKMT2ATDP1KDRRAB9A | |
| SCHEMBL21291437 | 0.78 | MEN1 (0.34) | KMT2ARAB9ANPC1 | |
| SCHEMBL21291310 | 0.78 | NTRK1 (0.33) | POLBKMT2AKDRRAB9ANPC1 | |
| SCHEMBL21291439 | 0.75 | RIPK2 (0.38) | POLBKMT2ATDP1RAB9A | |
| SCHEMBL21291407 | 0.74 | EGLN1 (0.42) | — | |
| SCHEMBL17080280 | 0.73 | ALDH1A1 (0.44) | POLBKMT2ATDP1 | |
| SCHEMBL19984596 | 0.72 | ROCK1 (0.41) | POLBKDR | |
| SCHEMBL18667838 | 0.72 | MAPT (0.41) | POLBKMT2AKDR | |
| SCHEMBL18667833 | 0.71 | ALDH1A1 (0.49) | POLBKMT2AKDR | |
| SCHEMBL17080158 | 0.70 | MAPT (0.42) | POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053157-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2018-03-22 | — | — | WO | disclosed |