Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.54 |
| ▸ | FEN1 | P39748 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.49 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.49 |
| ▸ | CHRNG | P07510 | 2/20 | 0.49 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.49 |
| ▸ | CHRND | Q07001 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13647196 | 0.88 | ERCC5 (0.56) | ERCC5FEN1MEN1KMT2APARP1 | |
| SCHEMBL7400231 | 0.83 | MEN1 (0.56) | ERCC5FEN1MEN1KMT2APARP1 | |
| SCHEMBL19984703 | 0.83 | ERCC5 (0.54) | ERCC5FEN1MEN1KMT2APARP1 | |
| SCHEMBL7406071 | 0.83 | KMO (0.66) | ERCC5FEN1MEN1KMT2APARP1 | |
| SCHEMBL728409 | 0.83 | KMO (0.66) | ERCC5FEN1MEN1KMT2APARP1 | |
| SCHEMBL3675550 | 0.83 | KMO (0.66) | ERCC5FEN1MEN1KMT2APARP1 | |
| SCHEMBL10600107 | 0.81 | ERCC5 (0.49) | ERCC5FEN1MEN1KMT2APARP1 | |
| SCHEMBL8812764 | 0.81 | CTNNB1 (0.53) | MEN1KMT2APARP1SLC6A2SLC6A3 | |
| SCHEMBL5082697 | 0.79 | NPC1 (0.54) | ERCC5FEN1PARP1SLC6A2SLC6A3 | |
| SCHEMBL12237073 | 0.79 | ERCC5 (0.47) | ERCC5FEN1MEN1KMT2APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2306986-B1 | PRODRUGS AND DRUG-MACROMOLECULE CONJUGATES HAVING CONTROLLED DRUG RELEASE RATES | PROLYNX LLC (US) | 2018-03-21 | — | — | EP | disclosed |