Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18667774 | 0.91 | TP53 (0.48) | EGLN1TP53MAPTSMN1; SMN2RXFP1 | |
| SCHEMBL21291409 | 0.88 | EGLN1 (0.42) | EGLN1ROCK2KMT2APOLBTDP1 | |
| SCHEMBL21291308 | 0.88 | EGLN1 (0.40) | EGLN1ROCK2 | |
| SCHEMBL19984640 | 0.85 | SLC22A12 (0.35) | EGLN1ROCK2 | |
| SCHEMBL18667797 | 0.82 | TP53 (0.47) | EGLN1TP53MAPTSMN1; SMN2RXFP1 | |
| SCHEMBL19984597 | 0.82 | POLB (0.44) | ROCK2TP53MAPTSMN1; SMN2RXFP1 | |
| SCHEMBL19984756 | 0.81 | ROCK2 (0.40) | ROCK2TP53MAPTSMN1; SMN2RXFP1 | |
| SCHEMBL18667815 | 0.81 | EGLN1 (0.45) | EGLN1ROCK2 | |
| SCHEMBL19984599 | 0.80 | POLB (0.46) | ROCK2TP53MAPTSMN1; SMN2RXFP1 | |
| SCHEMBL18667183 | 0.80 | TP53 (0.51) | TP53MAPTSMN1; SMN2RXFP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053157-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2018-03-22 | — | — | WO | disclosed |