Succinimide

Succinimide

SCHEMBL1998492

O=C1C=CC(=O)N1.O=C1CCC(=O)N1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 9/20 0.65
GSK3A P49840 1/20 0.65
GSK3B P49841 1/20 0.65
CCR6 P51684 1/20 0.65
NPC1 O15118 1/20 0.39
MAPK13 O15264 1/20 0.39
MAPK12 P53778 1/20 0.39
MAPK11 Q15759 1/20 0.39
MAPK14 Q16539 1/20 0.39
CA9 Q16790 1/20 0.34
SRD5A1 P18405 1/20 0.32
MAPT P10636 1/20 0.32
DDB1 Q16531 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinimide SCHEMBL6231913 0.97 CRBN (0.61) CRBNGSK3AGSK3BCCR6NPC1
SCHEMBL10990 0.80
SCHEMBL7021498 0.80
SCHEMBL33524954 0.80
Succinimide SCHEMBL1466558 0.80
Succinimide SCHEMBL8361206 0.80 CRBN (1.00) CRBNGSK3AGSK3BNPC1MAPK13
Succinimide SCHEMBL774 0.80
SCHEMBL693917 0.80 GSK3B (1.00) GSK3AGSK3BCCR6
SCHEMBL1599522 0.80
SCHEMBL715867 0.80 GSK3B (1.00) GSK3AGSK3BCCR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110090635-B GSH affinity chromatography medium for purifying GST-tag fusion protein, and preparation method and application thereof 武汉菲恩生物科技有限公司 2021-11-16 CN claimed
CN-110090635-A A kind of GSH affinity chromatography medium and its preparation method and application purifying GST-tag fusion protein 武汉菲恩生物科技有限公司 2019-08-06 CN claimed
CN-110090635-B GSH affinity chromatography medium for purifying GST-tag fusion protein, and preparation method and application thereof 武汉菲恩生物科技有限公司 2021-11-16 CN disclosed
CN-110090635-B GSH affinity chromatography medium for purifying GST-tag fusion protein, and preparation method and application thereof 武汉菲恩生物科技有限公司 2021-11-16 CN disclosed
EP-3484521-B1 POLY(L-LYSINE ISOPHTHALAMIDE) (PLP) POLYMERS WITH HYDROPHOBIC PENDANT CHAINS ALPHACELLS BIOTECHNOLOGIES LTD (GB) 2021-04-07 EP disclosed
US-20190248956-A1 POLY(L-LYSINE ISOLPHTHALAMIDE) (PLP) POLYMERS WITH HYDROPHOBIC PENDANT CHAINS IMPERIAL INNOVATIONS LIMITED (GB) 2019-08-15 US disclosed
CN-110121362-A Poly- (lysine isophtalamide) (PLP) polymer with hydrophobic side chain 帝国理工大学创新有限公司 2019-08-13 CN disclosed
US-10370652-B2 Methods of nucleic acid amplification and sequencing ILLUMINA, INC. (US) 2019-08-06 US disclosed
CN-110090635-A A kind of GSH affinity chromatography medium and its preparation method and application purifying GST-tag fusion protein 武汉菲恩生物科技有限公司 2019-08-06 CN disclosed
CN-110090635-A A kind of GSH affinity chromatography medium and its preparation method and application purifying GST-tag fusion protein 武汉菲恩生物科技有限公司 2019-08-06 CN disclosed
US-10357751-B2 Polymer micelles containing nanoparticles in non-aqueous solution, methods for their preparation and use FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2019-07-23 US disclosed
EP-0708337-A2 Analysis element and method for analyzing glycated hemoglobin content ratio FUJI PHOTO FILM CO., LTD. (JP) 1996-04-24 EP disclosed
US-5447846-A Homogeneous Immunoassay process using covalent conjugate of enzyme and plural monoclonal antibodies for different epitopes on analyte FUJI PHOTO FILM C., LTD. (JP) 1995-09-05 US disclosed
US-5352583-A A first monoclonal antibody bonded to insoluble solid carrier; a second polyclonal antibody labelled by an enzyme; diluent; detergent TEIJIN LIMITED (JP) 1994-10-04 US disclosed
EP-0579250-A2 Homogeneous immunoassay, enzyme-labelled antibody and element FUJI PHOTO FILM CO., LTD. (JP) 1994-01-19 EP disclosed
EP-0339302-B1 Reagent system for immunologically assaying complex of human plasminogen activator inhibitor and human tissue plasminogen activator, and assay kit therefor TEIJIN LTD (JP) 1993-12-22 EP disclosed
EP-0423333-A1 ANTI-ENDOSERINE ANTIBODY Yamasa Shoyu Kabushiki Kaisha (JP) 1991-04-24 EP disclosed
EP-0339302-A1 Reagent system for immunologically assaying complex of human plasminogen activator inhibitor and human tissue plasminogen activator, and assay kit therefor TEIJIN LIMITED (JP) 1989-11-02 EP disclosed
EP-0180141-B1 PROCESS FOR MAKING DIENE POLYMER RUBBERS NIPPON ZEON CO., LTD. (JP) 1989-08-30 EP disclosed
US-4629683-A STORAGE STABILITY AND TIMELY RELEASE OF PHOTOGRAPHICALLY USEFUL AGENT FUJI PHOTO FILM CO., LTD. (JP) 1986-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190248956-A1 POLY(L-LYSINE ISOLPHTHALAMIDE) (PLP) POLYMERS WITH HYDROPHOBIC PENDANT CHAINS PLP2, LNPEP, PLPBP CRBN 2700/4885GSK3A 3727/4885GSK3B 3906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.