Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.51 |
| ▸ | FEN1 | P39748 | 1/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 6/20 | 0.45 |
| ▸ | WNT3A | P56704 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16313440 | 0.85 | ERCC5 (0.51) | ERCC5FEN1CTNNB1WNT3AHPGD | |
| SCHEMBL13647199 | 0.81 | ERCC5 (0.55) | ERCC5FEN1CTNNB1WNT3AHPGD | |
| SCHEMBL3704844 | 0.78 | ERCC5 (0.60) | ERCC5FEN1CTNNB1WNT3AHPGD | |
| SCHEMBL19984929 | 0.78 | ERCC5 (0.51) | ERCC5FEN1HPGDKMT2AMEN1 | |
| SCHEMBL8053673 | 0.76 | ERCC5 (0.58) | ERCC5FEN1CTNNB1WNT3AHPGD | |
| SCHEMBL30089517 | 0.76 | CTNNB1 (0.68) | ERCC5FEN1CTNNB1WNT3AHPGD | |
| SCHEMBL15979740 | 0.76 | CTNNB1 (0.68) | ERCC5FEN1CTNNB1WNT3AHPGD | |
| SCHEMBL8735550 | 0.76 | ERCC5 (0.74) | ERCC5FEN1CTNNB1WNT3AHPGD | |
| SCHEMBL8535216 | 0.75 | ERCC5 (0.53) | ERCC5FEN1CTNNB1WNT3AHPGD | |
| SCHEMBL193821 | 0.75 | ERCC5 (0.49) | ERCC5FEN1CTNNB1WNT3AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2306986-B1 | PRODRUGS AND DRUG-MACROMOLECULE CONJUGATES HAVING CONTROLLED DRUG RELEASE RATES | PROLYNX LLC (US) | 2018-03-21 | — | — | EP | disclosed |