Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.74 |
| ▸ | FEN1 | P39748 | 1/20 | 0.74 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.53 |
| ▸ | WNT3A | P56704 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269381 | 0.90 | ERCC5 (0.68) | ERCC5FEN1NPC1KMT2AMEN1 | |
| SCHEMBL29483365 | 0.90 | ERCC5 (0.68) | ERCC5FEN1NPC1KMT2AMEN1 | |
| SCHEMBL3660192 | 0.89 | ERCC5 (0.72) | ERCC5FEN1NPC1KMT2AMEN1 | |
| SCHEMBL8383887 | 0.89 | ERCC5 (0.67) | ERCC5FEN1NPC1KMT2AMEN1 | |
| SCHEMBL17867035 | 0.87 | ERCC5 (0.65) | ERCC5FEN1NPC1KMT2AMEN1 | |
| SCHEMBL30089517 | 0.86 | CTNNB1 (0.68) | ERCC5FEN1NPC1KMT2AMEN1 | |
| SCHEMBL15979740 | 0.86 | CTNNB1 (0.68) | ERCC5FEN1NPC1KMT2AMEN1 | |
| SCHEMBL3166061 | 0.86 | ERCC5 (0.62) | ERCC5FEN1NPC1KMT2AMEN1 | |
| SCHEMBL13684611 | 0.86 | ERCC5 (0.62) | ERCC5FEN1NPC1KMT2AMEN1 | |
| SCHEMBL8348768 | 0.84 | ERCC5 (0.61) | ERCC5FEN1NPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614916-B1 | Process for producing polyolefin | IDEMITSU PETROCHEMICAL CO (JP) | 1998-10-07 | — | — | EP | claimed |
| US-5605990-A | USING CATALYST COMPRISING TITANIUM COMPOUND, ALUMINOXANE, AROMATIC RING-CONTAINING COMPOUND | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1997-02-25 | — | — | US | claimed |
| EP-0614916-A1 | Process for producing polyolefin | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1994-09-14 | — | — | EP | claimed |
| CN-110143935-B | Preparation method of 2, 5-disubstituted furan derivative | 华侨大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-115093323-A | Beta-functionalized chiral homoallyl alcohol derivative and preparation method and application thereof | 武汉大学 | 2022-09-23 | — | — | CN | disclosed |
| CN-107126660-B | Composition containing fluoroketone | 中化蓝天集团有限公司 | 2021-02-05 | — | — | CN | disclosed |
| EP-3122735-B1 | 3-PHENYL-7-HYDROXY-ISOCOUMARINS AS MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) INHIBITORS | THE PROVOST FELLOWS FOUND SCHOLARS AND THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIV (IE) | 2019-05-08 | — | — | EP | disclosed |
| US-20190071410-A1 | 3-Phenyl-7-Hydroxy-Isocoumarins as Macrophage Migration Inhibitory Factor (MIF) Inhibitors | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2019-03-07 | — | — | US | disclosed |
| US-20170144983-A1 | 3-Phenyl-7-Hydroxy-Isocoumarins as Macrophage Migration Inhibitory Factor (MIF) Inhibitors | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2017-05-25 | — | — | US | disclosed |
| US-20170144983-A1 | 3-Phenyl-7-Hydroxy-Isocoumarins as Macrophage Migration Inhibitory Factor (MIF) Inhibitors | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2017-05-25 | — | — | US | disclosed |
| US-9371422-B2 | Titanium containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2016-06-21 | — | — | US | disclosed |
| US-20140213690-A1 | Titanium Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts | DOW CORNING CORPORATION (US) | 2014-07-31 | — | — | US | disclosed |
| WO-2013036546-A2 | TITANIUM CONTAINING COMPLEX AND CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING CORPORATION (US) | 2013-03-14 | — | — | WO | disclosed |
| EP-0614916-B1 | Process for producing polyolefin | IDEMITSU PETROCHEMICAL CO (JP) | 1998-10-07 | — | — | EP | disclosed |
| US-5605990-A | USING CATALYST COMPRISING TITANIUM COMPOUND, ALUMINOXANE, AROMATIC RING-CONTAINING COMPOUND | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1997-02-25 | — | — | US | disclosed |
| EP-0614916-A1 | Process for producing polyolefin | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1994-09-14 | — | — | EP | disclosed |
| EP-0598134-A1 | PROCESS FOR PRODUCING POLYOLEFIN | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1994-05-25 | — | — | EP | disclosed |
| EP-0362012-B1 | Stabiliser compositions for halogenated polymers containing beta-diketone, hydrotalcite and dihydropyridine, and polymers stabilized therewith | ATOCHEM ELF SA (FR) | 1993-12-29 | — | — | EP | disclosed |
| EP-0362012-A1 | Stabiliser compositions for halogenated polymers containing beta-diketone, hydrotalcite and dihydropyridine, and polymers stabilized therewith | ELF ATOCHEM S.A. (FR) | 1990-04-04 | — | — | EP | disclosed |
| US-4036605-A | CATALYZING OXIDATION OF HYDROCARBONS WITH A B-KETOENOLATE | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1977-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170144983-A1 | 3-Phenyl-7-Hydroxy-Isocoumarins as Macrophage Migration Inhibitory Factor (MIF) Inhibitors | MIF, CCL2, MMP12 | ERCC5 3229/4885FEN1 2564/4885NPC1 184/4885 |
| US-20190071410-A1 | 3-Phenyl-7-Hydroxy-Isocoumarins as Macrophage Migration Inhibitory Factor (MIF) Inhibitors | MIF, CCL2, MMP12 | ERCC5 3229/4885FEN1 2564/4885NPC1 184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.