SCHEMBL19985074

SCHEMBL19985074

CCCCN[SiH2]O[SiH2]NC

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
EPHX1 P07099 1/20 0.32
ADH1B P00325 1/20 0.30
ADH1C P00326 1/20 0.30
ADH1A P07327 1/20 0.30
ADH7 P40394 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19985002 0.91 TSHR (0.31) TSHREPHX1
SCHEMBL20130854 0.91 TSHR (0.39) TSHREPHX1ADH1BADH1CADH1A
SCHEMBL22489297 0.80 TSHR (0.32) TSHR
SCHEMBL28621095 0.74 TSHR (0.31) TSHR
SCHEMBL20130879 0.71
SCHEMBL20127098 0.71
SCHEMBL25260185 0.68 ACHE (0.35) TSHREPHX1
SCHEMBL19973261 0.68 TSHR (0.33) TSHRADH1BADH1CADH1AADH7
SCHEMBL17409612 0.66 TSHR (0.45) TSHREPHX1ADH1BADH1CADH1A
SCHEMBL888678 0.66 TSHR (0.45) TSHREPHX1ADH1BADH1CADH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018053129-A1 COMPOSITIONS AND METHODS FOR THE DEPOSITION OF SILICON OXIDE FILMS VERSUM MATERIALS US, LLC (US) 2018-03-22 WO disclosed