Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22907692 | 0.86 | ESR1 (0.36) | EPHX2 | |
| SCHEMBL22907539 | 0.85 | EPHX2 (0.30) | EPHX2 | |
| SCHEMBL22907478 | 0.80 | EPHX2 (0.35) | EPHX2 | |
| SCHEMBL13854228 | 0.75 | EPHX2 (0.42) | EPHX2 | |
| SCHEMBL13854238 | 0.71 | EPHX2 (0.46) | EPHX2 | |
| SCHEMBL18651737 | 0.68 | EPHX2 (0.46) | EPHX2 | |
| SCHEMBL13854220 | 0.65 | EPHX2 (0.44) | EPHX2 | |
| SCHEMBL4198695 | 0.62 | EPHX2 (0.57) | EPHX2 | |
| SCHEMBL13854232 | 0.60 | SMYD3 (0.32) | — | |
| SCHEMBL28345621 | 0.58 | MAOA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2944310-B1 | MIF inhibitors for the acute or chronic treatment of pulmonary hypertension | MIFCARE (FR) | 2018-03-21 | — | — | EP | disclosed |