Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 4/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18134257 | 1.00 | S1PR1 (0.33) | S1PR1FPR2FFAR4TGFBR1ACVR1 | |
| SCHEMBL19985372 | 0.90 | KDM1A (0.33) | FPR2FFAR4ESR2ESR1CYP3A4 | |
| SCHEMBL19985387 | 0.90 | FPR2 (0.35) | S1PR1FPR2FFAR4TGFBR1ACVR1 | |
| SCHEMBL19985406 | 0.89 | DGAT1 (0.35) | S1PR1FPR2FFAR4TGFBR1ACVR1 | |
| SCHEMBL18134256 | 0.87 | S1PR1 (0.33) | S1PR1FPR2FFAR4TGFBR1ACVR1 | |
| SCHEMBL19985377 | 0.87 | FPR2 (0.33) | FPR2FFAR4 | |
| SCHEMBL19985380 | 0.86 | FFAR4 (0.34) | FFAR4CYP2C9 | |
| SCHEMBL19985381 | 0.85 | FFAR4 (0.32) | S1PR1FPR2FFAR4 | |
| SCHEMBL18134254 | 0.84 | DGAT1 (0.34) | FFAR4DGAT1SOAT1ESR2ESR1 | |
| SCHEMBL17614852 | 0.84 | FPR2 (0.37) | S1PR1FPR2FFAR4TGFBR1ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079959-A1 | LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY | DIC CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |
| US-20180079959-A1 | LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY | DIC CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |