SCHEMBL19985384

SCHEMBL19985384

CC/C=C\CC1CCC(c2ccc(-c3ccc(OCC)c(F)c3F)cc2)CC1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 3/20 0.35
KDM1A O60341 2/20 0.33
GRIN1 Q05586 1/20 0.32
GRIN2B Q13224 1/20 0.32
FGFR1 P11362 1/20 0.31
FGFR2 P21802 1/20 0.31
ESR1 P03372 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
ESR2 Q92731 1/20 0.31
FFAR4 Q5NUL3 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19985390 0.92 FPR2 (0.34) FPR2
SCHEMBL19985385 0.91 RAB9A (0.32) FPR2CYP2C9FFAR4
SCHEMBL19985387 0.91 FPR2 (0.35) FPR2ESR1CYP3A4CYP2C9ESR2
SCHEMBL19985372 0.91 KDM1A (0.33) FPR2KDM1AGRIN1GRIN2BFGFR1
SCHEMBL19985399 0.91 SPHK1 (0.31) FPR2
SCHEMBL19985391 0.90 SPHK1 (0.33) FPR2
SCHEMBL19985405 0.90 SPHK1 (0.33) FPR2
SCHEMBL19985393 0.90 SPHK1 (0.33) FPR2
SCHEMBL19985392 0.90 SPHK1 (0.33) FPR2
SCHEMBL17715213 0.88 KDM1A (0.37) FPR2KDM1AGRIN1GRIN2BFGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180079959-A1 LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY DIC CORPORATION (JP) 2018-03-22 US disclosed
US-20180079959-A1 LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY DIC CORPORATION (JP) 2018-03-22 US disclosed