Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | PON1 | P27169 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13760085 | 0.86 | PTGS2 (0.36) | PTGS2ADORA3MAOBPTGS1MEN1 | |
| SCHEMBL21577512 | 0.85 | HDAC3 (0.34) | HPGDALDH1A1TDP1L3MBTL1 | |
| SCHEMBL8932533 | 0.82 | PSMB5 (0.40) | MAOBMEN1NPC1RAB9AKMT2A | |
| SCHEMBL18573626 | 0.82 | HDAC3 (0.33) | — | |
| SCHEMBL13760089 | 0.81 | PTGS2 (0.40) | PTGS2ADORA3MAOBPTGS1MEN1 | |
| SCHEMBL20783364 | 0.81 | — | — | |
| SCHEMBL803431 | 0.77 | PTGS2 (0.40) | PTGS2ADORA3MAOBPTGS1MEN1 | |
| SCHEMBL19321529 | 0.77 | ESR2 (0.39) | — | |
| SCHEMBL8932519 | 0.77 | ADORA3 (0.40) | PTGS2ADORA3MAOBPTGS1MEN1 | |
| SCHEMBL14211939 | 0.76 | PTGS2 (0.39) | PTGS2ADORA3MAOBPTGS1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079959-A1 | LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY | DIC CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |