SCHEMBL19986063

SCHEMBL19986063

c1ccc(-n2c3ccccc3c3c(-c4ccc(-n5c6ccccc6c6c7c8ccccc8c8ccccc8c7c7c8ccccc8oc7c65)cc4)cccc32)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ALDH1A1 P00352 3/20 0.33
PPARG P37231 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
NR2E3 Q9Y5X4 1/20 0.33
NCOR2 Q9Y618 1/20 0.33
ALOX5 P09917 1/20 0.33
POLB P06746 2/20 0.32
MEN1 O00255 1/20 0.32
TSHR P16473 1/20 0.32
BRCA1 P38398 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CDC14B O60729 2/20 0.32
CDC14A Q9UNH5 2/20 0.32
LMNA P02545 1/20 0.32
HDAC4 P56524 1/20 0.31
CA12 O43570 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19986090 0.92 ALOX5 (0.34) KDM4EATML3MBTL1ALDH1A1PPARG
SCHEMBL19986054 0.91 KDM4E (0.35) KDM4EATML3MBTL1ALDH1A1PPARG
SCHEMBL19986076 0.91 KDM4E (0.37) KDM4EATML3MBTL1ALDH1A1PPARG
SCHEMBL19986067 0.89 ALOX5 (0.44) KDM4EATMALDH1A1PPARGRXFP1
SCHEMBL19986019 0.88 ENPP3 (0.33) KDM4EL3MBTL1ALDH1A1ALOX5HSD17B10
SCHEMBL19986007 0.87 KDM4E (0.37) KDM4EATML3MBTL1ALDH1A1PPARG
SCHEMBL19986042 0.87 KDM4E (0.37) KDM4EATML3MBTL1ALDH1A1PPARG
SCHEMBL19986016 0.87 KDM4E (0.44) KDM4EATML3MBTL1ALDH1A1PPARG
SCHEMBL19986101 0.87 ALOX5 (0.33) ALOX5CDC14BCDC14A
SCHEMBL19986086 0.86 BRDT (0.34) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed