SCHEMBL19986124

SCHEMBL19986124

c1ccc(-c2cccc(-c3cc(-c4ccccc4)cc(-n4c5ccccc5c5c6c7ccccc7c7ccccc7c6c6c7ccccc7oc6c54)n3)c2)cc1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 1/20 0.31
PLA2G4A P47712 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
CYP3A4 P08684 1/20 0.31
ALPI P09923 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31
HPGD P15428 1/20 0.31
CASP3 P42574 1/20 0.31
RECQL P46063 1/20 0.31
BLM P54132 1/20 0.31
CASP7 P55210 1/20 0.31
CASP6 P55212 1/20 0.31
KMT2A Q03164 1/20 0.31
MCL1 Q07820 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19986125 0.95 MAPT (0.32) NPC1RAB9AKDM4EMEN1CYP3A4
SCHEMBL19986126 0.94 MEN1 (0.32) NPC1RAB9AKDM4EMEN1CYP3A4
SCHEMBL19986200 0.87 PLA2G2A (0.32) PLA2G2APLA2G4AMEN1MAPTKMT2A
SCHEMBL19986127 0.86 MEN1 (0.32) KDM4EMEN1CYP3A4ALPIGAA
SCHEMBL19986149 0.85 KDM4E (0.37) PLA2G2APLA2G4ANPC1RAB9AKDM4E
SCHEMBL19986008 0.82 PLA2G2A (0.35) PLA2G2APLA2G4AKDM4EMEN1PKM
SCHEMBL19986020 0.82 PLA2G2A (0.38) PLA2G2APLA2G4AKDM4EMEN1KMT2A
SCHEMBL19986018 0.81 MEN1 (0.35) PLA2G2APLA2G4ANPC1RAB9AKDM4E
SCHEMBL19986121 0.81 MAPT (0.35) PLA2G2APLA2G4AKDM4EMEN1CYP3A4
SCHEMBL19986123 0.81 ADORA2A (0.33) PLA2G2APLA2G4ANPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed