SCHEMBL19986165

SCHEMBL19986165

Cc1nc(-c2cccc3c2sc2ccccc23)c2ccccc2n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP14 Q460N5 1/20 0.43
ALOX5 P09917 1/20 0.43
ADORA2A P29274 4/20 0.42
MAPT P10636 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.39
ATM Q13315 1/20 0.39
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
PRKDC P78527 3/20 0.37
PIK3CD O00329 1/20 0.37
PIK3CB P42338 1/20 0.37
GPR3 P46089 1/20 0.36
TLR8 Q9NR97 1/20 0.35
TLR7 Q9NYK1 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25162370 0.84 ALOX5 (0.39) PARP14ALOX5ADORA2AMAPTL3MBTL1
SCHEMBL14233770 0.83 KDM4E (0.46) PARP14ALOX5ADORA2AMAPTLMNA
SCHEMBL19986166 0.83 ADORA2A (0.42) ADORA2AMAPTL3MBTL1LMNAHTT
SCHEMBL19655097 0.81 MAPT (0.47) PARP14ALOX5ADORA2AMAPTL3MBTL1
SCHEMBL18415772 0.79 PARP14 (0.47) PARP14ALOX5MAPTL3MBTL1ATM
SCHEMBL20110484 0.79 PARP14 (0.47) PARP14ALOX5MAPTL3MBTL1ATM
SCHEMBL18455698 0.78 KDM4E (0.43) PARP14ALOX5ADORA2AMAPTLMNA
SCHEMBL16542822 0.77 ADORA2A (0.50) ADORA2ALMNAHTTGPR3MEN1
SCHEMBL29985983 0.77 ADORA2A (0.50) ADORA2ALMNAHTTGPR3MEN1
SCHEMBL24596451 0.77 ADORA2A (0.47) PARP14ALOX5ADORA2AMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240025927-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-25 US disclosed
US-20240025927-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-25 US disclosed
US-20230389421-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-30 US disclosed
EP-4282863-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-11-29 EP disclosed
US-20230363276-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 US disclosed
US-20230363276-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 US disclosed
US-20230286989-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-20230286989-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-20230192714-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 US disclosed
US-20230192714-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 US disclosed
US-20230124902-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-20 US disclosed
US-20230023360-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-01-26 US disclosed
US-20220336747-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-10-20 US disclosed
US-20220281898-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-09-08 US disclosed
US-20220140256-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-05-05 US disclosed
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220336747-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP PARP14 3637/4885ALOX5 256/4885ADORA2A 3371/4885
US-20220140256-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, INMT PARP14 1091/4885ALOX5 178/4885ADORA2A 887/4885
US-20230363276-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 PARP14 321/4885ALOX5 634/4885ADORA2A 2339/4885
US-20230124902-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 PARP14 2760/4885ALOX5 88/4885ADORA2A 3228/4885
US-20230286989-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 PARP14 2336/4885ALOX5 145/4885ADORA2A 3169/4885
US-20230192714-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 PARP14 2305/4885ALOX5 142/4885ADORA2A 2746/4885
US-20220281898-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, OXSR1, C1R PARP14 3006/4885ALOX5 1335/4885ADORA2A 1658/4885
US-20240025927-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 PARP14 2974/4885ALOX5 486/4885ADORA2A 4406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.