Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 11/20 | 0.67 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986174 | 0.97 | TOP1 (0.71) | TOP1PRMT5DHODHCYP1A2KDM4E | |
| SCHEMBL19986177 | 0.91 | TOP1 (0.59) | TOP1PRMT5CYP1A2 | |
| SCHEMBL19844332 | 0.82 | TOP1 (0.82) | TOP1DHODHKDM4EALDH1A1HPGD | |
| SCHEMBL18020161 | 0.80 | TOP1 (1.00) | TOP1DHODHHSD17B10 | |
| SCHEMBL18731749 | 0.78 | CYP1A2 (0.58) | CYP1A2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL18538846 | 0.76 | TOP1 (0.46) | TOP1CYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL19986168 | 0.75 | DHODH (0.51) | TOP1DHODHCYP1A2KDM4EALDH1A1 | |
| SCHEMBL1104820 | 0.74 | CYP1A2 (0.62) | CYP1A2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8284604 | 0.74 | PRMT5 (0.68) | TOP1PRMT5CYP1A2KDM4EALDH1A1 | |
| SCHEMBL21511856 | 0.74 | CCR1 (0.51) | TOP1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180083202-A1 | COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE | SAMSUNG SDI CO., LTD. (KR) | 2018-03-22 | — | — | US | disclosed |