SCHEMBL19986174

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19986179	0.97	TOP1 (0.67)	TOP1PRMT5CYP1A2DHODHNCF1
	SCHEMBL19986177	0.91	TOP1 (0.59)	TOP1PRMT5CYP1A2MAPTPDE4A
	SCHEMBL18020161	0.83	TOP1 (1.00)	TOP1DHODHHSD17B10
	SCHEMBL19844332	0.81	TOP1 (0.82)	TOP1DHODHKDM4EALDH1A1HPGD
	SCHEMBL18538846	0.78	TOP1 (0.46)	TOP1CYP1A2KDM4EALDH1A1HPGD
	SCHEMBL8284604	0.77	PRMT5 (0.68)	TOP1PRMT5CYP1A2NCF1KDM4E
	SCHEMBL1104820	0.77	CYP1A2 (0.62)	CYP1A2NCF1KDM4EALDH1A1HPGD
	SCHEMBL21511856	0.76	CCR1 (0.51)	TOP1KDM4EALDH1A1HPGDHSD17B10
	Iodide SCHEMBL30847747	0.75	CYP1A2 (0.60)	CYP1A2NCF1KDM4EALDH1A1HPGD
	SCHEMBL7440672	0.75	CCR1 (0.57)	TOP1KDM4EALDH1A1CCR1CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.