SCHEMBL1998634

SCHEMBL1998634

CC(O)c1ccc(F)c(F)c1F

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.50
CES1 P23141 3/20 0.50
PDE2A O00408 3/20 0.37
F2RL1 P55085 3/20 0.34
ADRB2 P07550 2/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
NPC1 O15118 1/20 0.33
KCNH2 Q12809 1/20 0.32
ADRA2A P08913 3/20 0.32
ADRA2B P18089 3/20 0.32
ADRA2C P18825 3/20 0.32
ADRA1A P35348 2/20 0.32
ADRA1B P35368 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8282823 0.82 PDE2A (0.35) CES2CES1PDE2AADRB2ADRB1
SCHEMBL28650506 0.80 PDE2A (0.46) CES2CES1PDE2AF2RL1ADRB2
SCHEMBL12049608 0.80 CES2 (0.44) CES2CES1PDE2ANPC1ADRA1A
SCHEMBL7627962 0.80 CES2 (0.53) CES2CES1PDE2AF2RL1ADRB2
SCHEMBL23363630 0.79 CES2 (0.52) CES2CES1ADRB1ADRB3ADRA2A
SCHEMBL29757453 0.79 CES2 (0.52) CES2CES1ADRB1ADRB3ADRA2A
SCHEMBL30846991 0.79 CES2 (0.52) CES2CES1ADRB1ADRB3ADRA2A
SCHEMBL1993389 0.79 CES2 (0.52) CES2CES1ADRB1ADRB3ADRA2A
SCHEMBL27904303 0.79 CES2 (0.52) CES2CES1ADRB1ADRB3ADRA2A
SCHEMBL10302847 0.79 ADRB2 (0.43) CES2CES1PDE2AADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US disclosed
CN-102186921-B Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2014-01-15 CN disclosed
EP-2338935-B1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS CO LTD (JP) 2012-12-12 EP disclosed
US-20110172336-A1 FLUOROCOPOLYMER COMPOSITION AND ITS PRODUCTION PROCESS ASAHI GLASS COMPANY, LIMITED (JP) 2011-07-14 US disclosed
EP-2338935-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2011-06-29 EP disclosed
EP-1369475-A1 Microbiological process for enantioselective (S)-hydroxylation Bayer Aktiengesellschaft (DE) 2003-12-10 EP disclosed