SCHEMBL19986362

SCHEMBL19986362

C=CCCOc1ccc(C2CCC(C3CCCCC3)CC2)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 4/20 0.33
PRCP P42785 1/20 0.33
KDM4E B2RXH2 1/20 0.32
PTGDR Q13258 1/20 0.31
FEN1 P39748 2/20 0.31
ALOX5AP P20292 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21451531 0.95 PTGDR2 (0.34) PTGDR2PRCPKDM4EPTGDRFEN1
SCHEMBL21451516 0.92 PTGDR2 (0.34) PTGDR2PRCPKDM4EPTGDR
SCHEMBL12140874 0.89 KDM4E (0.34) KDM4E
SCHEMBL30093781 0.89 KDM4E (0.34) KDM4E
SCHEMBL19986385 0.88 FEN1 (0.37) PTGDR2PTGDRFEN1ALOX5AP
SCHEMBL18517278 0.87 HTR2C (0.38) PTGDR2PRCPPTGDR
SCHEMBL19985280 0.87
SCHEMBL4402626 0.85 ALDH1A1 (0.31)
SCHEMBL12733641 0.85 KDM4E (0.36) KDM4E
SCHEMBL23968127 0.84 KDM4E (0.36) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11522141-B2 Electronic switching element MERCK PATENT GMBH (DE) 2022-12-06 US disclosed
US-20210292651-A1 ELECTRONIC SWITCHING ELEMENT MERCK PATENT GMBH (DE) 2021-09-23 US disclosed
US-20180079959-A1 LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY DIC CORPORATION (JP) 2018-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11522141-B2 Electronic switching element DNMT3A, DNMT1, DNMT3B PTGDR2 293/4885PRCP 4752/4885KDM4E 2993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.