SCHEMBL19986385

SCHEMBL19986385

C=CCCOc1ccc(-c2ccc(C3CCCCC3)c(F)c2F)c(F)c1F

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FEN1 P39748 16/20 0.37
ALOX5AP P20292 10/20 0.37
PTGDR2 Q9Y5Y4 4/20 0.36
PTGDR Q13258 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19985585 0.88 KDM4E (0.34) FEN1ALOX5AP
SCHEMBL19986362 0.88 PTGDR2 (0.33) FEN1ALOX5APPTGDR2PTGDR
SCHEMBL19986380 0.87 HTR2C (0.38) FEN1ALOX5APPTGDR2PTGDR
SCHEMBL19985591 0.86 FPR2 (0.32) FEN1ALOX5AP
SCHEMBL19985595 0.84 GABRA1 (0.31) FEN1ALOX5AP
SCHEMBL19986348 0.83 CYP3A4 (0.36) FEN1ALOX5APPTGDR2PTGDR
SCHEMBL21451531 0.82 PTGDR2 (0.34) FEN1ALOX5APPTGDR2PTGDR
SCHEMBL12733897 0.82 ALOX5AP (0.35) FEN1ALOX5AP
SCHEMBL19985601 0.82 SCN9A (0.32) FEN1ALOX5AP
SCHEMBL12733641 0.82 KDM4E (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180079959-A1 LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY DIC CORPORATION (JP) 2018-03-22 US disclosed