Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986440 | 0.78 | TDP1 (0.50) | TDP1CYP1A2CYP2D6APEX1PMP22 | |
| SCHEMBL13540012 | 0.76 | TDP1 (0.35) | TDP1CYP1A2CYP2D6 | |
| SCHEMBL25095029 | 0.76 | SLC6A4 (0.37) | TDP1 | |
| SCHEMBL24465537 | 0.76 | TDP1 (0.35) | TDP1CYP1A2CYP2D6 | |
| SCHEMBL9913299 | 0.76 | — | — | |
| SCHEMBL2737422 | 0.76 | — | — | |
| SCHEMBL104635 | 0.76 | — | — | |
| SCHEMBL20099378 | 0.75 | ADH1B (0.32) | TDP1 | |
| SCHEMBL25449211 | 0.75 | LMNA (0.30) | TDP1 | |
| SCHEMBL19969869 | 0.74 | TDP1 (0.33) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3587417-B9 | 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES | BAYER AG (DE) | 2022-03-30 | — | — | EP | disclosed |