SCHEMBL19986695

SCHEMBL19986695

CCc1cncc(C)c1NC

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.34
NOS1 P29475 1/20 0.34
NOS2 P35228 1/20 0.34
KCNH2 Q12809 1/20 0.33
SCN5A Q14524 1/20 0.33
AOC1 P19801 1/20 0.31
AOC3 Q16853 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7126030 0.73 NOS3 (0.39) NOS3NOS1NOS2AOC3
SCHEMBL7124851 0.71 NOS3 (0.38) NOS3NOS1NOS2
SCHEMBL15109313 0.70 NOS3 (0.36) NOS3NOS1NOS2
SCHEMBL14493554 0.70 NOS3 (0.36) NOS3NOS1NOS2
SCHEMBL18125581 0.70 NOS3 (0.45) NOS3NOS1NOS2
SCHEMBL20326527 0.69 NOS3 (0.38) NOS3NOS1NOS2AOC3
SCHEMBL2868352 0.68 SCN5A (0.50) KCNH2SCN5A
SCHEMBL23872809 0.67 NOS3 (0.34) NOS3NOS1NOS2
Hydrochloric Acid SCHEMBL2868350 0.67 PTGS2 (0.49) KCNH2SCN5A
SCHEMBL21718967 0.67 NOS3 (0.34) NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018050110-A1 NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR 正大天晴药业集团股份有限公司 2018-03-22 WO disclosed