Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21292640 | 0.91 | LMNA (0.37) | KMT2ALMNAKDM4EALDH1A1POLB | |
| SCHEMBL19987089 | 0.91 | KMT2A (0.40) | KMT2ALMNAKDM4EALDH1A1POLB | |
| SCHEMBL19987088 | 0.91 | KMT2A (0.40) | KMT2ALMNAKDM4EALDH1A1POLB | |
| SCHEMBL19987010 | 0.88 | LMNA (0.35) | KMT2ALMNAKDM4EALDH1A1POLB | |
| SCHEMBL19986903 | 0.88 | KMT2A (0.46) | KMT2ALMNAKDM4EALDH1A1POLB | |
| SCHEMBL21292633 | 0.88 | KMT2A (0.46) | KMT2ALMNAKDM4EALDH1A1POLB | |
| SCHEMBL19987136 | 0.88 | KMT2A (0.46) | KMT2ALMNAKDM4EALDH1A1POLB | |
| SCHEMBL19971470 | 0.88 | KMT2A (0.46) | KMT2ALMNAKDM4EALDH1A1POLB | |
| SCHEMBL22591922 | 0.87 | ALDH1A1 (0.35) | KMT2AKDM4EALDH1A1POLBPDE2A | |
| SCHEMBL21292696 | 0.85 | KDM4E (0.43) | KMT2ALMNAKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050510-A1 | 7-SUBSTITUTED 1-ARYL-NAPHTHYRIDINE-3-CARBOXYLIC ACID AMIDES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-03-22 | — | — | WO | disclosed |