Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29981071 | 0.94 | LMNA (0.41) | IMPDH2LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL21292626 | 0.94 | LMNA (0.41) | IMPDH2LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL19986885 | 0.89 | KMT2A (0.40) | IMPDH2LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL19987081 | 0.84 | LMNA (0.41) | IMPDH2LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL19987049 | 0.83 | IMPDH2 (0.41) | IMPDH2LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL29457321 | 0.83 | IMPDH2 (0.41) | IMPDH2LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL19986944 | 0.83 | KMT2A (0.43) | IMPDH2LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL19986980 | 0.81 | KDM4E (0.46) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL19986876 | 0.81 | KDM4E (0.46) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL19971376 | 0.81 | KDM4E (0.46) | LMNACYP2C9ATP6V1B2TBXA2REDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050510-A1 | 7-SUBSTITUTED 1-ARYL-NAPHTHYRIDINE-3-CARBOXYLIC ACID AMIDES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-03-22 | — | — | WO | disclosed |