Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | DUT | P33316 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23992637 | 0.88 | TOP2A (0.38) | TOP2AMAPTHPGDDUT | |
| SCHEMBL19974561 | 0.86 | TOP2A (0.37) | TOP2AMAPTHPGDDUT | |
| SCHEMBL12150953 | 0.74 | LMNA (0.43) | TOP2ADUT | |
| SCHEMBL23034558 | 0.74 | LMNA (0.43) | TOP2ADUT | |
| SCHEMBL19987250 | 0.74 | TOP2A (0.37) | TOP2ADUT | |
| SCHEMBL19866492 | 0.74 | TOP2A (0.35) | TOP2AMAPTHPGD | |
| SCHEMBL23225591 | 0.74 | TOP2A (0.35) | TOP2AMAPTHPGD | |
| SCHEMBL22700152 | 0.73 | TOP2A (0.49) | TOP2ADUT | |
| SCHEMBL26558122 | 0.73 | TOP2A (0.33) | TOP2AMAPTHPGDCYP3A4 | |
| SCHEMBL13526167 | 0.73 | TOP2A (0.37) | TOP2ADUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018049535-A1 | NUCLEOSIDE ANALOGUES AND METHODS OF USE THEREOF | LCB PHARMA INC. (CA) | 2018-03-22 | — | — | WO | disclosed |