Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.57 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.51 |
| ▸ | JAK2 | O60674 | 2/20 | 0.50 |
| ▸ | JAK1 | P23458 | 2/20 | 0.50 |
| ▸ | TYK2 | P29597 | 2/20 | 0.50 |
| ▸ | JAK3 | P52333 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2687107 | 0.84 | KMT2A (0.60) | HSD17B10KMT2AKDM4EHTTPTGER4 | |
| SCHEMBL1063039 | 0.84 | KMT2A (0.63) | HSD17B10KMT2AKDM4EHTTPTGER4 | |
| SCHEMBL22442338 | 0.82 | HCAR3 (0.59) | HSD17B10EHMT2EHMT1KMT2AKDM4E | |
| SCHEMBL1731013 | 0.81 | KMT2A (0.76) | HSD17B10KMT2AMEN1KDM4EPOLB | |
| SCHEMBL540958 | 0.80 | TNF (0.73) | KMT2AMEN1KDM4EPOLBHTT | |
| SCHEMBL6169101 | 0.80 | KDM4E (0.59) | HSD17B10KMT2AMEN1KDM4EPOLB | |
| SCHEMBL6840412 | 0.80 | RAB9A (0.60) | HSD17B10KMT2AKDM4EHTTPTGER4 | |
| SCHEMBL31072768 | 0.79 | PPARG (0.55) | HSD17B10KMT2AMEN1KDM4EHTT | |
| SCHEMBL29342745 | 0.79 | PPARG (0.55) | HSD17B10KMT2AMEN1KDM4EHTT | |
| SCHEMBL708371 | 0.79 | POLB (0.54) | EHMT2EHMT1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053161-A1 | NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS D-AMINO ACID OXIDASE (DAAO) INHIBITORS | NATIONAL TAIWAN UNIVERSITY (TW) | 2018-03-22 | — | — | WO | disclosed |