SCHEMBL19987388

SCHEMBL19987388

Cc1cc(C)c(Nc2ccc(C)c(O)c2)c(C)c1

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19993558 0.84 RAPGEF4 (0.57) RAPGEF4
SCHEMBL17858133 0.82 RAPGEF4 (0.69) RAPGEF4
SCHEMBL11516096 0.80 RAPGEF4 (0.73) RAPGEF4
SCHEMBL19985671 0.78 RAPGEF4 (0.54) RAPGEF4
SCHEMBL15188815 0.77 RAPGEF4 (1.00) RAPGEF4
SCHEMBL801391 0.75 RAPGEF4 (0.79) RAPGEF4
SCHEMBL7555415 0.74 HPGD (0.54)
SCHEMBL19985677 0.74 TYR (0.57) RAPGEF4
SCHEMBL20414251 0.74 RAPGEF4 (0.59) RAPGEF4
SCHEMBL22848481 0.73 RAPGEF4 (0.68) RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10723969-B2 Lubricant compositions stabilized by mixtures of diarylamine and hydroxydiarylamine antioxidants LANXESS SOLUTIONS US INC. (US) 2020-07-28 US disclosed
US-20180079987-A1 LUBRICANT COMPOSITIONS STABILIZED BY MIXTURES OF DIARYLAMINE AND HYDROXYDIARYLAMINE ANTIOXIDANTS LANXESS SOLUTIONS US INC. 2018-03-22 US disclosed