SCHEMBL22848481

SCHEMBL22848481

Cc1cc(C)c(Nc2ccc3cc(C)ccc3c2)c(C)c1

nearest known ligand 0.68

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 19/20 0.68
CYP1A2 P05177 1/20 0.50
CYP2A6 P11509 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22848405 0.87 RAPGEF4 (0.60) RAPGEF4
SCHEMBL15188815 0.81 RAPGEF4 (1.00) RAPGEF4
SCHEMBL17732417 0.79 SNCA (0.62) RAPGEF4CYP1A2CYP2A6
SCHEMBL17858133 0.78 RAPGEF4 (0.69) RAPGEF4
SCHEMBL17880362 0.78 RAPGEF4 (0.53) RAPGEF4CYP1A2CYP2A6
SCHEMBL18734414 0.76 RAPGEF4 (0.72) RAPGEF4
SCHEMBL801391 0.75 RAPGEF4 (0.79) RAPGEF4
SCHEMBL20342387 0.74 CYP2A6 (0.68) CYP1A2CYP2A6
SCHEMBL19987388 0.73 RAPGEF4 (0.62) RAPGEF4
SCHEMBL22340283 0.73 RAPGEF4 (1.00) RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11171165-B2 Photoelectric conversion element, imaging element, optical sensor comprising a photoelectric conversion film containing a predetermined compound, and compound FUJIFILM CORPORATION (JP) 2021-11-09 US disclosed
US-20200411569-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2020-12-31 US disclosed